B12 / "Cyanokobalamin ist giftg"…

When treated with vitamin B12, patients with Leber's disease may suffer rapid optic atrophy.

Gorilla schrieb:@ restausverkauf

Du hast Links zur Krankheit, aber wo ist der Zusammenhang zwischen Cyano und der verlinkten Krankheit?

Auf Wikipedia finde ich das hier:

When treated with vitamin B12, patients with Leber's disease may suffer rapid optic atrophy.

http://en.wikipedia.org/wiki/Cyanocobalamin#Possible_side_effects

Ich finde jetzt nicht, daß es sich exklusiv um die Lebersche Optikusatrophie handelt.

Gorilla schrieb:Auf Wikipedia finde ich das hier:

When treated with vitamin B12, patients with Leber's disease may suffer rapid optic atrophy.

http://en.wikipedia.org/wiki/Cyanocobalamin#Possible_side_effects

Wikipedia schrieb:When treated with vitamin B12, patients with Leber's disease may suffer rapid optic atrophy.[citation needed]

Ottomane schrieb:
Eine Aussage auf Wiki über ein nichttriviales Thema ohne Quelle ist erstmal ein Gerücht.

PLASMA-COBALAMINS IN NEURO-OPHTHALMOLOGICAL DISEASES

J. Wilson a b, J.C. Linnell b, D.M. Matthews b

Plasma-cyanocobalamin levels were found to be significantly raised in Leber's hereditary optic atrophy, dominantly inherited optic atrophy, tobacco amblyopia, and sporadic cases of optic atrophy. This change may be evidence of inborn metabolic errors of cyanide detoxication, varying clinically and genetically according to the particular enzyme involved.

M.R.C. Clinical Genetics Research Unit, at the Institute of Child Health, and Institute of Neurology, London W.C.1, United Kingdom

Department of Experimental Chemical Pathology, Westminster Medical School, London S.W.1, United Kingdom

As a result of the development and application of the chromo-bioautographic method of
estimating individual plasma-cobalamins in neuro-ophthalmological disorders, it may in the future be
possible to identify patients at risk in genetically determined disorders, such as Leber's optic atrophy