Startseite
Okay das ganze wird zwar hauptsächlich ein Copy-Paste Beitrag, aber diese Kombination von l-Alanin und l-Glycin in dem folgendem Getränk sorgt bei mir für einen so enormen Pump während des Trainings, dass ich es euch alleine schon wegen des Spaßfaktors nicht vorenthalten möchte 
Die weiteren Vorteile dieser Kombination könnt ihr unten lesen. Ich habe diese beiden Aminosäuren bei Amino-factory bekommen, falls jemand keine Bezugsquelle dafür findet.
Ich will noch erwähnen, dass der Effekt noch um einiges stärker eintritt, wenn man auf leeren Magen trainiert also morgens vor dem Frühstück und in einem Zustand ist, bei dem die Insulinausschüttung sehr gering ist. Z.B. nach einer reinen Eiweißmahlzeit.
Man merkt richtig, wie das Wasser in die Muskelzelle hineingezogen wird, anstatt nur im Blutkreislauf zu bleiben. Ich lege es jedem nahe diese Kombination mal auszuprobieren, die Erfahrung ist einfach geil
Cellular Hydration (swell) drink
NOTE you can lower the water quantity * and either reduce the quantity or eliminate the L-Glutamine ** if you can not tolerate it. You can also eliminate the Lemon Juice and coconut water if you need to.
What you can not eliminate is the L-Glycine & L-Alanine... and you should try to get in at least some L-Glutamine. These are the components of the intracellular pulling in of water. You need plenty of water as well. The L-Leucine is an anabolic amino acid and will benefit muscle by it's presence during the time of swell. The coconut water provides a nice mix of minerals and electrolytes which is often lacking in plain water. The Lemon Juice is for pH balance but is not needed. It is primarily a good flavoring system when combined with KAL brand of stevia (yes it is the best tasting stevia by far).
I mix the following drink to increase cellular swell during my workout:
6 grams of L-Leucine
4 grams of L-Alanine
3 grams of L-Glycine
8 - 25 grams of L-Glutamine **
75 ml of coconut water or plain water
75 ml of Lemon Juice
in 2 liters * of water.
I do get noticeably more swollen in the gym when I use this mix.
The science is stickied in this forum at: Cell Swelling/Cell Shrinkage by Dat
Here is a brief run down.
Muscle cellular swelling (cellular hydration) is anabolic
Cell volume and hydration status is always in flux. It is not possible to constantly maintain a cellular swell. Yet research has demonstrated that the signaling cascade that takes place in the cell as a result of swelling resembles the response initiated by growth factors. Cellular swelling is an anabolic signal triggering protein anabolism and hindering catabolism. When muscle cell water content is elevated protein synthesis is stimulated and when water content is decreased, protein synthesis is inhibited and protein degradation increases.
Cellular volume decreases after exercise and after everyday life stresss (many simply normal body functions). When cells shrink due to oxidative and exercise-induced stress, glucagon activation and high urea concentration we end up with:
• Decrease in glycogen synthesis
• Decrease in glutamine uptake by inactivating transporters
• Decrease in taurine efflux (outflow)
• Increase in the rate of release of glutamine and alanine from muscle
• Increase in protein breakdown
Cellular volume increases in response to hormones, insulin and high concentrations of L-glutamine, creatine, glycine, alanine, and glucose. When cells swell we end up with a:
• Increase in glycogen synthesis
• Increase in glutamine transporters, and therefore uptake
In turn when we have a decrease in rate of release of glutamine and alanine from muscle we end up with:
• Increase in taurine efflux by activating taurine transport pathways
• Decrease in protein breakdown and increase in synthesis
• Stimulation of urea synthesis and ammonia formation from amino acids
• Decrease in glycogenolysis, glycolysis and glucose-6-phosphatase activity
• Increase in alanine uptake
• Increase in glycine oxidation
• Increase in lipogenesis by decreasing carnitine palmitoyl transferase
Cell Volume Regulation
The increased concentration of amino acids and potassium during cell shrinkage eventually leads to swelling, which triggers volume regulatory decrease (potassium efflux). At maximum swelling, inositol, betaine, and taurine efflux begin as the cell begins a regulatory decrease in cell volume.
"However, as long as the amino acid load is present, the cell swelling continues, because the potassium, taurine, and other osmolyte efflux keep the swelling from becoming excessive. Therefore, in the presence of certain "organic osmolytes" (such as specific amino acids, alanine, glutamine, glysine), the cell remains slightly swollen, thus transmitting the signals associated with high cellular hydration (such as Protien synthesis). The degree of amino acid-induced cell swelling seems to be related largely to the steady state of the intra- or extracellular amino acid concentration gradient." - Neal F. Spruce and C. Alan Titchenal, Sports Nutrition: Fats and Proteins
Just how cellular swelling creates an increase in protein metabolism is not specifically known. The most likely reason is centered on the mechanisms involved in cytoskeleton (cell stretching), regulatory proteins, and stretch-activated cation and anion channels.
Usage
For many toggles cellular swelling will play a role. The intake of Alanine, Glutamine as well as Glycine should be beneficial. The only downside is that swelling can increase lipogenesis by decreasing carnitine palmitoyl transferase. This can be worked around.
Die weiteren Vorteile dieser Kombination könnt ihr unten lesen. Ich habe diese beiden Aminosäuren bei Amino-factory bekommen, falls jemand keine Bezugsquelle dafür findet.
Ich will noch erwähnen, dass der Effekt noch um einiges stärker eintritt, wenn man auf leeren Magen trainiert also morgens vor dem Frühstück und in einem Zustand ist, bei dem die Insulinausschüttung sehr gering ist. Z.B. nach einer reinen Eiweißmahlzeit.
Man merkt richtig, wie das Wasser in die Muskelzelle hineingezogen wird, anstatt nur im Blutkreislauf zu bleiben. Ich lege es jedem nahe diese Kombination mal auszuprobieren, die Erfahrung ist einfach geil
Cellular Hydration (swell) drink
NOTE you can lower the water quantity * and either reduce the quantity or eliminate the L-Glutamine ** if you can not tolerate it. You can also eliminate the Lemon Juice and coconut water if you need to.
What you can not eliminate is the L-Glycine & L-Alanine... and you should try to get in at least some L-Glutamine. These are the components of the intracellular pulling in of water. You need plenty of water as well. The L-Leucine is an anabolic amino acid and will benefit muscle by it's presence during the time of swell. The coconut water provides a nice mix of minerals and electrolytes which is often lacking in plain water. The Lemon Juice is for pH balance but is not needed. It is primarily a good flavoring system when combined with KAL brand of stevia (yes it is the best tasting stevia by far).
I mix the following drink to increase cellular swell during my workout:
6 grams of L-Leucine
4 grams of L-Alanine
3 grams of L-Glycine
8 - 25 grams of L-Glutamine **
75 ml of coconut water or plain water
75 ml of Lemon Juice
in 2 liters * of water.
I do get noticeably more swollen in the gym when I use this mix.
The science is stickied in this forum at: Cell Swelling/Cell Shrinkage by Dat
Here is a brief run down.
Muscle cellular swelling (cellular hydration) is anabolic
Cell volume and hydration status is always in flux. It is not possible to constantly maintain a cellular swell. Yet research has demonstrated that the signaling cascade that takes place in the cell as a result of swelling resembles the response initiated by growth factors. Cellular swelling is an anabolic signal triggering protein anabolism and hindering catabolism. When muscle cell water content is elevated protein synthesis is stimulated and when water content is decreased, protein synthesis is inhibited and protein degradation increases.
Cellular volume decreases after exercise and after everyday life stresss (many simply normal body functions). When cells shrink due to oxidative and exercise-induced stress, glucagon activation and high urea concentration we end up with:
• Decrease in glycogen synthesis
• Decrease in glutamine uptake by inactivating transporters
• Decrease in taurine efflux (outflow)
• Increase in the rate of release of glutamine and alanine from muscle
• Increase in protein breakdown
Cellular volume increases in response to hormones, insulin and high concentrations of L-glutamine, creatine, glycine, alanine, and glucose. When cells swell we end up with a:
• Increase in glycogen synthesis
• Increase in glutamine transporters, and therefore uptake
In turn when we have a decrease in rate of release of glutamine and alanine from muscle we end up with:
• Increase in taurine efflux by activating taurine transport pathways
• Decrease in protein breakdown and increase in synthesis
• Stimulation of urea synthesis and ammonia formation from amino acids
• Decrease in glycogenolysis, glycolysis and glucose-6-phosphatase activity
• Increase in alanine uptake
• Increase in glycine oxidation
• Increase in lipogenesis by decreasing carnitine palmitoyl transferase
Cell Volume Regulation
The increased concentration of amino acids and potassium during cell shrinkage eventually leads to swelling, which triggers volume regulatory decrease (potassium efflux). At maximum swelling, inositol, betaine, and taurine efflux begin as the cell begins a regulatory decrease in cell volume.
"However, as long as the amino acid load is present, the cell swelling continues, because the potassium, taurine, and other osmolyte efflux keep the swelling from becoming excessive. Therefore, in the presence of certain "organic osmolytes" (such as specific amino acids, alanine, glutamine, glysine), the cell remains slightly swollen, thus transmitting the signals associated with high cellular hydration (such as Protien synthesis). The degree of amino acid-induced cell swelling seems to be related largely to the steady state of the intra- or extracellular amino acid concentration gradient." - Neal F. Spruce and C. Alan Titchenal, Sports Nutrition: Fats and Proteins
Just how cellular swelling creates an increase in protein metabolism is not specifically known. The most likely reason is centered on the mechanisms involved in cytoskeleton (cell stretching), regulatory proteins, and stretch-activated cation and anion channels.
Usage
For many toggles cellular swelling will play a role. The intake of Alanine, Glutamine as well as Glycine should be beneficial. The only downside is that swelling can increase lipogenesis by decreasing carnitine palmitoyl transferase. This can be worked around.
